MGH Division of Clinical Research

A Practical Introduction to Statistical Genetics: Statistical Fine-Mapping

Ended: Sept. 23, 2020

Topics: goal of statistical fine-mapping; partitioning and interpreting GWAS lead signals; factors influencing fine-mapping (sample size, number of causal SNPs, effect sizes of causal SNPs, local LD structure, SNP density); statistical methods and software (heuristic methods, penalized regression, Bayesian methods); trans-ethnic fine-mapping; incorporating functional information (annotation, eQTL, etc) and functional follow-up

Speaker: Hailiang Huang

Program:
A Practical Introduction to Statistical Genetics

Category:
Genomics

Sponsor:
MGH Division of Clinical Research

Sessions

Sept. 23, 2020 09/23/20
9:30AM-11AM 		9:30 AM – 11 AM
STRATUS Online Moodle, None

Other Offerings

Past Offerings
A Practical Introduction to Statistical Genetics: Statistical Fine-Mapping Sept. 25, 2019 09/25/19

Reviews

Md Mesbah U:
Overall:
Content:
Instructor(s):
Experience:
Date Attended: Sept. 23, 2020, 10:19 a.m.
Date Reviewed: Sept. 30, 2020, 9:46 a.m.
Jasneet A:
Overall:
Content:
Instructor(s):
Experience:
Date Attended: Sept. 23, 2020, 10:17 a.m.
Date Reviewed: Sept. 24, 2020, 10:16 a.m.
Xudong H: The instructor is extremely knowledgeable about the topic. I truly enjoyed his lecture!
Overall:
Content:
Instructor(s):
Experience:
Date Attended: Sept. 23, 2020, 10:24 a.m.
Date Reviewed: Sept. 23, 2020, 12:06 p.m.
Bethany Z:
Overall:
Content:
Instructor(s):
Experience:
Date Attended: Sept. 23, 2020, 10:13 a.m.
Date Reviewed: Sept. 23, 2020, 11:20 a.m.
Jingnan D:
Overall:
Content:
Instructor(s):
Experience:
Date Attended: Sept. 23, 2020, 10:17 a.m.
Date Reviewed: Sept. 23, 2020, 11:03 a.m.
Anonymous:
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 23, 2020, 11:03 a.m.
Anonymous:
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 23, 2020, 10:17 a.m.
Anonymous:
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 25, 2019, 4:49 p.m.
Jianhai G:
Overall:
Content:
Instructor(s):
Experience:
Date Attended: Sept. 25, 2019, 9:55 a.m.
Date Reviewed: Sept. 25, 2019, 3:42 p.m.
Anonymous:
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 25, 2019, 3:41 p.m.
Anonymous: would be very helpful to have the slides in advance
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 25, 2019, 1:02 p.m.
Anonymous:
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 25, 2019, 10:45 a.m.
Anonymous: Good overview!
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 25, 2019, 10:11 a.m.
Anonymous: Good explanation of the role of fine-mapping and methods for using it. However, would have been very helpful to have the slides in advance. Also would be helpful to delve a bit deeper into the different search methods (exhaustive, greedy, stochastic). Thanks!
Overall:
Content:
Instructor(s):
Experience:
Date Reviewed: Sept. 25, 2019, 10:09 a.m.
Yiwen Z: Very informative!
Overall:
Content:
Instructor(s):
Experience:
Date Attended: Sept. 25, 2019, 9:55 a.m.
Date Reviewed: Sept. 25, 2019, 9:58 a.m.